Cytokine

Recombinant Mouse M-CSF

Catalog #: RP0003

Manufacturer: Reed Biotech

Size: 50 μg500 μg

Price: on inquiry

Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Storage
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C f…

Cell Culture & Bioassays

Product Details

Product Name Recombinant Mouse M-CSF Accesstion Number P07141
Alternative Names Macrophage colony-stimulating factor 1; CSF-1; MCSF; Csf1; Csfm
Description Recombinant Mouse Macrophage Colony-Stimulating Factor 1 is produced by our Mammalian expression system and the target gene encoding Lys33-Glu262 is expressed.
Calculated Molecular Weight Mol Mass:26 KDa; APMol Mass:37-80 KDa, reducing conditions Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Endotoxin < 0.01 EU/µg as determined by LAL test. Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Biological Activity Measured in a cell proliferation assay using M‑NFS‑60 mouse myelogenous leukemia lymphoblast cells.The ED50 for this effect is 0.04-0.2 ng/ml. (QC verified)
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Background Macrophage colony-stimulating factor 1(M-csf)is a single-pass type I membrane protein . It is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor, M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.
  • Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
  • Measured in a cell proliferation assay using M‑NFS‑60 mouse myelogenous leukemia lymphoblast cells.The ED50 for this effect is 0.04-0.2 ng/ml. (QC verified)

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Product Recombinant Mouse M-CSF Catalog #: RP0003
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